Effect of Proarginine Technology Plus 1450 PPM Fluoride on Enamel Reminerlization: An in Vitro Study

AIM: The objective of this in vitro study was to evaluate the effects of new dentifrices containing 1.5% arginine, an insoluble calcium compound, and fluoride for their ability to promote remineralization of demineralized enamel. Methods: Twenty human premolar extracted for orthodontic reasons were used. The specimens were immersed in demineralization solution followed by application of proargigne paste with fluoride. All the samples were assessed using DIAGNOdent at the baseline and after demineralization and remineralization and was statistical analyzed by using one way anova test. Results: There was statistically significant increase in the DIAGNodent ® values after remineralization of the tooth with a p value <0.001.The results of this in vitro study support the conclusion that dentifrices containing 1.5% arginine, an insoluble calcium compound, and 1450 ppm fluoride provide superior protection against caries lesion and have remineralization potential to reverse early enamel lesion. However more, randomized clinical trials are needed to be designed in order to test the efficacy of this product.